"His goggles were supposed to give me color vision, but instead they gave me some fancy color-based powers. I was bitter...sore.... Crime became my outlet."
The Rainbow Raider, Flash #286.
There are an estimated 20 million people in the U.S. with some form of colorblindness. Do they do anything cool about it? No, they just run around in ill-coordinated outfits and mismatched socks; Aquaman is one of them.
But a supervillain like the Rainbow Raider is a role model for us. He takes a handicap that barely exceeds the level of inconvenience, elevates it to a life-altering grudge, and uses it to give a purpose to his life: color-coordinated crime, color that he can't even see.
Much like Joe Coyne (see the Penny Plunderer), Roy G. Bivolo is a supervillain because he turns his own weakness into his strength; the very bane of his existence becomes the purpose of his life. Who says crime is not an art?